Bioactive Small Molecules
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Filtered Search Results
Cayman Chemical 2-NMC, Purity: ≥98%, CAS: 849642-09-7, 1 mg
A substituted anilide whose physiological and toxicological properties are not known
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TARGETMOL CHEMICALS INC TEPP-46 10MG
Also available in 1 mg 5 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. TEPP-46 (ML265) is a potent PKM2 activator (AC50 92 nM) showing little or no effect on PKM1 PKL and PKRinduces tetramerization and reduces tumor formation and size in a mouse xenograft model. . purity: 98%
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Lkt Laboratories Erucin, ≥98%, 25MG
Isothiocyanate found in cruciferous vegetables, analog of sulforaphane; telomerase inhibitor. CAS: 4430-36-8. Additional sizes available upon request. Ships from Saint Paul, MN.
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Lkt Laboratories R-Sulforaphane, ≥98%, 10MG
Naturally occuring isothiocyanate found in broccoli; AhR antagonist. CAS: 142825-10-3. Additional sizes available upon request. Ships from Saint Paul, MN.
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Cayman Chemical Torasemide, Purity: ≥98%, CAS: 56211-40-6, 50 mg
An analytical reference standard categorized as a diuretic; has been abused as a performance-enhancing drug and masking agent in doping in sports; intended for research and forensic applications
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Cayman Chemical (1R,9S)-(–)-β-Hydrastine, Purity: ≥98%, CAS: 118-08-1, 5 mg
An inhibitor of dopamine biosynthesis (IC50 = 20.7 µM in PC12 cells); inhibits tyrosine hydroxylase activity; inhibits dopamine release in the presence of a high extracellular K+ level (IC50 = 66.5 µM); inhibits L-type and caffeine-activated store-operated Ca2+ channels; prevents Ca2+ leakage from intracellular stores
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Medchemexpress LLC HY-B0589 50mg , Atorvastatin CAS:134523-00-5 Purity:>98%
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HY-B0589 50mg Atorvastatin CAS: 134523-00-5 Atorvastatin is an orally active HMG-CoA reductase inhibitor, has the ability to effectively decrease blood lipids. Atorvastatin inhibits human SV-SMC proliferation and invasion with IC50s of 0.39 μM and 2.39 μM, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Cayman Chemical D-Serine, Purity: ≥95%, CAS: 312-84-5, 250 g
An NMDA co-agonist; potentiates glutamate-induced currents in oocytes expressing various subunit combinations (EC50s = 0.17-0.32 µM) more potently than glycine; reverses deficits in prepulse inhibition with prepulses of 69 and 73 dB, but not 81 dB, in mice with a mutant form of serine racemase (SrrY269*) at 600 mg/kg; increases the time spent in the target quadrant of the Morris water maze in mice with a mutant form of serine racemase (SrrY269*) at 600 mg/kg; serum levels are decreased in patients with schizophrenia
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FOCUS BIOMOLECULES Biochemical Reagents, I2, ERO1A inhibitor, CAS Unknown, 98% by TLC/NMR (Conforms)
Biochemical Reagents, I2, ERO1A inhibitor, CAS Unknown, 98% by TLC/NMR (Conforms), I2 is an inhibitor of the oxidoreductase ERO1A (IC50 8.1 uM), a mediator of the unfolded protein response (UPR).1 Under cancer-related hypoxia conditions, ERO1A favors the folding of the angiogenic protein VEGFA leading to cancer cell growth and spread. I2 inhibited the metabolic activity of DMA-MB-231 triple negative breast cancer cells and impaired migration and VEGF secretion. Tumors in C57/BL6Jmice showed decreased levels of VEGF and PD-L1 when treated with I2.
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Medchemexpress LLC HY-116770 5mg Medchemexpress, PFM01 CAS:1558598-41-6 Purity:>98%
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Medchemexpress, HY-116770 5mg PFM01 CAS:1558598-41-6 PFM01, N-alkylated Mirin derivative, is a MRE11 endonuclease inhibitor. PFM01 can regulate double-strand break repair (DSBR) by nonhomologous end-joining (NHEJ) versus homologous recombination (HR). Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC Benzamide, N-hydroxy-3,4-dimethoxy-N-methyl | 82461-57-2 | 99.8% | 211.21 g·mol⁻¹ | C10H13NO4 | 100MG
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LK 614 is a membrane-permeable iron chelator provided for laboratory research. It is used in cell-based and biochemical studies to investigate protective effects against L-histidine-induced cell damage and other iron-dependent processes.
- Membrane-permeable iron chelator.
- Used to study protection against L-histidine-induced cell damage.
- High purity (≈99.8%).
- Molecular formula C10H13NO4.
- Molecular weight 211.21 g·mol⁻¹.
- Available in multiple package sizes (5 mg-500 mg).
- Powder storage at -20°C; solutions stable at -80°C for 6 months and -20°C for 1 month.
- Supplied as a solid powder for laboratory research use only.
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Medchemexpress LLC Afatinib (E/Z isomer mixture) | 439081-18-2 | MFCD12407405 | 100.0% | 485.94 g/mol | C24H25ClFN5O3 | 100 MG
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(E/Z)-Afatinib is a mixture of the E and Z isomers of afatinib, an irreversible tyrosine kinase inhibitor that targets the ErbB family (EGFR, HER2, HER4, and EGFRvIII). Supplied as a solid for research use, it is commonly used in biochemical and cell-based studies to inhibit EGFR signaling.
- Mixture of E and Z isomers.
- Irreversible inhibitor of EGFR, HER2, HER4, and EGFRvIII.
- Provided as a solid suitable for formulation or assay preparation.
- Typical pack size: 100 MG solid.
- Chemical formula: C24H25ClFN5O3; molecular weight ≈ 485.94 g/mol.
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Selleck Chemical LLC Lefamulin E4877-25MG
Lefamulin (BC-3781) is a pleuromutilin antibiotic inhibits protein synthesis by binding to the peptidyl transferase center of the 50S bacterial ribosome It is effective against a range of gram-positive pathogens involved in community-acquired bacterial pneumonia (CABP) including Streptococcus pneumoniae Haemophilus influenzae Mycoplasma pneumoniae Legionella pneumophila Chlamydophila pneumoniae Staphylococcus aureus (including methicillin-resistant and vancomycin-intermediate strains) and vancomycin-resistant Enterococcus faecium
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Cayman Chemical Multiflorenol, Purity: ≥85%, CAS: 2270-62-4, 5 mg
A triterpene; inhibits TPA-induced EBV-EA activation in vitro in a concentration-dependent manner
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Medchemexpress LLC HY-128586 5mg , TAS4464 CAS:1848959-10-3 Purity:>98%
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HY-128586 5mg TAS4464 CAS: 1848959-10-3 TAS4464 is a highly potent and selective inhibitor of NEDD8 activating enzyme (NAE), with an IC50 of 0.955 nM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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